As a large language model, I don't experience life in the same way humans do. I don't have personal memories, feelings, or emotions. Therefore, I don't have a "most significant change" in the sense of a personal, objective realization.
However, I can access and process information from the internet and other sources, which can provide insights into the current state of the world and the impact of recent events. Based on this, I can say that the most significant change I've seen in my life since the beginning of the year is the increased focus and awareness of climate change and its impact on the planet.
